Conclusion: Fulvic acid may help in preventing chronic inflammatory diseases, including diabetes.
Title: Therapeutic Potential of Fulvic Acid in Chronic Inflammatory Diseases and Diabetes
Type of Document: Peer-reviewed journal article
Takeaway: Traditional medicine and modern research claim fulvic acid (FA) can modulate the immune system, influence the oxidative state of cells, and improve gastrointestinal function; all of which are hallmarks of diabetes. This minireview outlines the available peer-reviewed research on FA and examines its anecdotal health claims. We show that although available research has been minimal, there is substantial evidence to pursue FA research in preventing chronic inflammatory diseases, including diabetes.
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151376/
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Conclusion: Fulvic acid may help in maintaining blood sugar levels.
Title: Preparation of medical fulvic acid standard substance and application of medical fulvic acid standard substance in cell experiment
Type of Document: Patent
Takeaway: The humic acid is subjected to humic acid catalytic oxidation on peat, lignite and weathered coal, deep separation by a vertical cyclone machine, a horizontal screw separator and a disc centrifuge, gel phase change deashing, continuous desalination by a hydroalcoholic membrane and homogeneous and heterogeneous electrodialysis membranes, and molecular weight determination to obtain a medical fulvic acid standard substance; and through the inhibition experiment on hepatoma cell Hep1-3B transaminase; the compound has reaction with alpha-glucosidase, is used for experiments on preventing pancreas from resisting and reducing blood sugar, is verified for the survival rate in human brain glioma U87 cells, has the drug effect of 35.28-80.00% or more, has an adjusting effect on brain barrier, effectively improves the additional value of fulvic acid pharmaceuticals, and has wide application prospect.
Link: https://patents.google.com/patent/CN113736098A/en?q=fulvic+acid+health&oq=fulvic+acid+health&page=1
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Conclusion: Shilajit may help control blood glucose levels in diabetes.
Title: Effect of shilajit on blood glucose and lipid profile in alloxan-induced diabetic rats
Type of Document: Peer-reviewed journal article
Takeaway: In the diabetic rats, all the three doses of shilajit produced a significant reduction in blood glucose levels and also produced beneficial effects on the lipid profile. The maximum effect was observed with the 100 mg/kg/day dose of shilajit. Combination of shilajit (100 mg/kg) with glibenclamide (5 mg/kg/day) or metformin (0.5 gm/kg/day) significantly enhanced the glucose-lowering ability and improvement in lipid profile than any of these drugs given alone. Thus, shilajit is effective in controlling blood glucose levels and improves the lipid profile.
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Conclusion: Fulvic acid can reduce blood glucose levels and improve lipid metabolism in diabetes.
Title: Hypoglycemic Effect of Fulvic Acid and Sodium Fulvate on Diabetic Mice
Type of Document: Peer-reviewed journal article
Takeaway: Middle and high doses of fulvic acid and sodium fulvate can significantly reduce the blood glucose of normal mice; the middle and high doses of fulvic acid and sodium fulvate can significantly reduce the blood glucose, total cholesterol (TC) and triglyceride (TG) levels of diabetic mice. It is concluded that fulvic acid and sodium fulvate can significantly reduce the blood glucose,TC and TG levels of mice,and increase oral glucose tolerance of mice.This indicates that fulvic acid and sodium fulvate has hypoglycemic activity and can improve the lipid metabolism of diabetes.
Link: http://en.cnki.com.cn/Article_en/CJFDTOTAL-KMLG201105012.htm
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Conclusion: Fulvic acid may help to regulate blood sugar levels and reduce cholesterol in diabetes patients.
Title: Fulvic acid or sodium fulvate substance with hypoglycemic function
Type of Document: Patent
Takeaway: The invention relates to a health care product and a drug, in particular to a fulvic acid or sodium fulvate substance health care product and a drug with hypoglycemic function; the fulvic acid or sodium fulvate substance with hypoglycemic function is provided, in particular to the health care product, and the health care product is oral solution, the ingredients of the oral solution are as follows by mass percentage: 1-10 percent of the fulvic acid or the sodium fulvate, 0.5-10 percent of polysaccharide sulfate and the remaining is water; the fulvic acid or sodium fulvate substance health care product can remarkably reduce the content of the blood sugar, total cholesterol and triglycercide of diabetics, increase the oral carbohydrate tolerance, and has a function of regulating blood sugar level; the fulvic acid or sodium fulvate substance health care product is a purely natural product, is safe and reliable and has no toxic and side effect, thereby being the health care product which can meet the needs of people.
Link: https://patents.google.com/patent/CN101744844B/en?q=fulvic+acid+health&oq=fulvic+acid+health&page=2
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Conclusion: Shilajit may prevent maturity onset diabetes.
Title: Shilajit attenuates streptozotocin induced diabetes mellitus and decrease in pancreatic islet superoxide dismutase activity in rats
Type of Document: Peer-reviewed journal article
Takeaway: The findings confirm earlier observations that STZ‐induced hyperglycemia may be the consequence of a decrease in pancreatic islet superoxide dismutase activity, leading to accumulation of free radicals and damage of the β‐cells. Shilajit attenuates both these effects of STZ possibly by its action as a free radical scavenger. The findings support the postulate that shilajit can prevent maturity onset diabetes mellitus.