Gut Health

Conclusion:  Humic acids, fulvic acids, and Shilajit may protect against intestinal injury.

Title: Protection against Gluten-mediated Tight Junction Injury with a Novel Lignite Extract Supplement

Type of Document: Peer-reviewed journal article

Takeaway: Naturally-oxidized lignite extracts including shilajit, humic acids and fulvic acids have been used as dietary supplements to deliver soil-based minerals and amino acids in China and India for hundreds of years.

Link: https://www.researchgate.net/publication/306959202_Protection_against_Gluten-mediated_Tight_Junction_Injury_with_a_Novel_Lignite_Extract_Supplement

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Conclusion:  Lignite extract supplement may protect against intestinal injury

Title: Protective Effects of Lignite Extract Supplement on Intestinal Barrier Function in Glyphosate-Mediated Tight Junction Injury

Type of Document: Peer-reviewed journal article

Takeaway: The lignite extract supplement RESTORE blocked a glyphosate-dependent decrease in TEER in both cell lines. If found efficacious in clinical trials, RESTORE could prove helpful in combating intestinal sensitivities caused by glyphosate mediated tight junction disruption.

Link: https://www.researchgate.net/publication/315966370_Protective_Effects_of_Lignite_Extract_Supplement_on_Intestinal_Barrier_Function_in_Glyphosate-Mediated_Tight_Junction_Injury

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Conclusion: Humic acids increase the population of beneficial gut bacteria.

Title: Impact of humic acids on the colonic microbiome in healthy volunteers

Type of Document: Peer-reviewed journal article

Takeaway: Humic acids have a profound effect on healthy colonic microbiome and may be potentially interesting substances for the development of drugs that control the innate colonic microbiome.

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296205/?fbclid=IwAR3gv9v470V56cyXn_4CH0u7nY8qrouOGiZ-kQ1UErfkBNRGOVgtN2rKM8A

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Conclusion:  Shilajit boosts energy and acts as a detoxifying agent.

Title: Shilajit: A Humic Matter Panacea for Cancer

Type of Document: Peer-reviewed journal article

Takeaway: Shilajit has been used for the treatment of hypersensitivity, diabetes, digestive disorder, nervous ailment, tuberculosis, chronic bronchitis, asthma, anemia,eczema, bone fractures, genitourinary ailment and many other diseases. Fulvic acid is the main constituent of Shilajit and along with FA and HA it also contains minerals in ionic form. These minerals are transported to cells and tissues by fulvic acid, which maintains the electric potential of the cells of the body and thus possibly prevents its death, provides longevity and might act as a rejuvenator. It helps in metabolism and energy production in the body. It can also act as a detoxifying agent in the body and can function as an immunomodulator and helps in haematopoiesis.

Link: https://www.academia.edu/5999580/Shilajit_A_Humic_Matter_Panacea_for_Cancer

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Conclusion:  Fulvic acid can improve gut microbiota and nutrient absorption, and heal gut disorders.

Title: Therapeutic Potential of Fulvic Acid in Chronic Inflammatory Diseases and Diabetes

Type of Document: Peer-reviewed journal article

Takeaway: In agriculture, fulvic acid (FA) has been shown to influence the soil microbe composition and be able to conjugate itself to various minerals, aiding in the uptake in plants. As a result, FA is suggested to improve the gut flora, nutrient absorption, and heal adverse disorders related to the gut.

Link: https://www.hindawi.com/journals/jdr/2018/5391014/

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Conclusion: Fulvic acid regulates gut health.

Title: Humic substances as a potent biomaterials for therapeutic and drug delivery system-a review

Type of Document: Review article

Takeaway: Immune modulating property of fulvic acid influence the redox state, and affect gut health.

Link: https://www.serravit.com.tr/wp-content/uploads/2020/08/Humic-substances-as-a-potent-biomaterials-for-therapeutic-and-drug-delivery-system-a-rewiev.pdf

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Conclusion: Fulvic and humic acids show therapeutic effects against gut health problems such as diarrhea, dysentery, and colitis.

Title: Medical drugs from humus matter: Focus on mumie.

Type of Document: Review article

Takeaway: With respect to internal use, fulvic and humic acids have been shown to be particularly useful in therapy for gastritis, diarrhea, stomach ulcers (antiulcerogenic and antistress activity), dysentery, colitis, and diabetes mellitus.

Link: https://sci-hub.se/10.1002/ddr.10058